… The differentiation of B cells from multipotent haematopoietic … lymphoid (ALP) and B-lymphoid
committed (BLP) progenitors … binding of complementary cis-gene regulatory elements …

… We compared normal B-lineage differentiation and in vivo leukemic cell states using single
cell RNA-sequencing (scRNA-seq) and several complementary genomics profiles. Based on …

… The blockage at the early B lymphoid cell development … , where the disruption of basal
regulatory networks prevents the … of three modules (ig differentiation genetic core, communication …

… but complementary signaling … differentiation of early BCP subsets. Collectively, our results
suggest impaired induction of the B-lymphoid fate as well as poor proliferation of early BCPs in …

… of myeloid differentiation) genes at various stages of B cell … cell fate reprogramming: B lymphoid
progenitors become T … of the highly diverse complementarity-determining region 3 (CDR3…

… regulation during T cell-lineage differentiation, we … genes. In the present study, our integrative
approach also revealed the complementarity of regulation by the different epigenetic layers …

… regulatory network remains poorly understood. Here, we show that the transcription factor ETS
Related Gene (Erg) is essential for early B lymphoid differentiation… to complement the loss …

… , and are therefore the earliest B-lymphoid restricted progenitors in the fetal B-… differentiation
genes (138). It is hypothesized that the proliferative capacity and complementary epigenetic …

… that they disturb the regulation of different subsets of genes, and … abolished when IK-3a is
overexpressed in B lymphoid cells. … This mechanism, which is based on the complementary …

… Hormones positively or negatively regulate the differentiation of B cells and the expression
of transcription factors, genes and cytokines that induce activation, apoptosis, or proliferation. …